Glucosamine (in sulfate-form!)

Along with minerals, micro nutrients and many amino acids sea shellfish contain high levels of glycosaminoglycans (GAG). One of the main components of GAG is the amino acid glucosamine. Shellfish contain higher levels of glucosamine, an important substance that gives bones, cartilage, hair etc. their structure.

Chondroitin (in sulfate-form!)

Shark skeletons contain large amounts of chondroitin. In other words, it makes sense to make use of the sharks caught in the fishing nets all over the world as “chondroitin donors”. Ideally, the entire shark skeleton is made of nothing but cartilage substances and can consequently be entirely used for the human body. As early as 1955, Dr. Serge Orloff of the University Hospital in Brussels was successful in his application of shark cartilage for his patients. Chondroitin binds the sulfur part, which is partly responsible for the osmotic suction in the cartilage-matrix and guarantees thereby the water binding capacity of the cartilage ground substance, leading among other things to the "elastic hardness" of cartilage ("principle of the restrictive bondage contra expansive swelling")

Methionine and Cysteine

Methionine and cysteine are important organic „sulfur donors“, and belong to the group of essential amino acids that are not produced by the human body, and therefore need to enter our bodies by nutrition intake. Sulfur compounds are especially necessary for many processes in human cells and can all, with the exception of sulfurous vitamins, be made out of methionine. In the cartilage and connective tissue the sulfur content, which is contributed by methionine and cysteine, concurs on the elastic hardness of the cartilage ("water magnet principle")

Manganese

Manganese deficiency often goes unnoticed, but in itself it can lead to an increase of osteoarthritis.